Paper Title: Comparing intraocular pressure and pachymeter adjusted intraocular pressure in a Sub-Saharan African cohort.
Authors: Odogu V, Awoyesuku E, Chinawa N.E, Anyiam F.
PURPOSE: To evaluate the effect of Central Corneal Thickness on measured intraocular pressure in a sub-Saharan cohort METHOD: Central corneal thickness CCT was measured by means of ultrasound pachymeter (IOPAC, Heidelberg Engineering, Germany) among subjects known to have glaucoma and those who did not have glaucoma. After instillation of topical anaesthetic, eight measurements were taken and the average value was recorded. The cohort of patients was those attending the outpatient department of the eye unit, university teaching hospital. Patients and controls were randomly selected. The Intra-ocular pressures were measured with Perkins Tonometer, after instillation of topical anaesthetic and flourescein eye drops. A total of 147 eyes were assessed, 50 eyes of which had glaucoma and 97 eyes were “normal” RESULTS: The average CCT for all patients was 513.7um ± 52.395. There was a progressive decrease in CCT with age in normal and glaucomatous subjects in line with previous studies. No linear relationship between IOP and age could be established among glaucomatous and normal subjects. There is inverse relationship between corneal thickness and IOP in normal and glaucomatous subjects. There was no clinical significant difference between Goldman measured IOP and pachymeter adjusted IOP CONCLUSION: There is decrease CCT with age in glaucomatous and non-glaucomatous subjects. There is also an inverse relationship between CCT and IOP leading to underestimation of IOP with thin corneas and vice versa in both glaucomatous and non glaucomatous eyes. There was no clinical significant difference between IOP measured by Goldmann and Pachymeter adjusted IOP