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Paper Title: Prevalence and pattern of depression among Parkinsons disease patients: A review

Authors: Ugbomah L.O., Oluwatayo O.M.,Princewill F.B.

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Parkinsons disease (PD) is the most common movement disorder affecting 1-2% of the general population from the age of 65yrs and above and the second most common neurodegenerative disorder after Alzheimers disease. Worldwide, studies indicate a wide range of occurrence of PD, with prevalence rates ranging from 31- 328/100,000 persons. It manifest with psychiatric disturbances, depression being the commonest causing significant functional impairment. Reported rate of depression in PD varies from 2.7% to 90% with average ranging from 40 to 50%. Most common risk factors for depression in PD include female sex, onset of parkinsonian symptoms before age 40, history of depression prior to diagnosis of PD, hypo- or bradykinesis, gait instability, greater functional disability, greater degree of left hemisphere involvement and disease severity. Depression is the main negative factor that impacts quality of life in PD. It is therefore crucial for depression in PD patients to be diagnosed because it is a treatable condition.

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